The heart does not have Alzheimer's disease: electrical and mechanical cardiac memory after ventricular pacing.

t has been known for some time that an altered sequence of entricular activation with a left bundle-branch conduction isturbance or right ventricular pacing is associated with a eduction in systolic and diastolic function manifested by ower ejection fraction and higher filling pressures. Furtherore, a variety of studies have shown that for a period of ime following cessation of the conduction disturbance resolution of left bundle branch block or discontinuance of entricular pacing), the heart manifests electrical and mehanical cardiac memory—persistent secondary repolarizaion changes and diastolic dysfunction.